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AEI currently utilizes a RIEGL VZ400 Terrestrial Laser Scanner on various job sites.  This proecss utilizes a high accuracy 3D terrestrial LiDAR unit.  The data collected will be brought into a feature extraction software, TopoDOT.  TopoDOT utilizes a variety of tools to identify adn quickly extrapolate features within pointcloud data.  All features can then be imported into an AutoCAD drawing file.  AEI can provide an accurate 3D pointcloud of terrain plus any existing building or structures.  The pointcloud can also be converted for Building Information Models.

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Allen Engineering is involved with the civil design and surveying for the new park in Palm Bay, Flordia.  This Regional Park will feature 150 full service campsite hookups and is scheduled to break ground in 2018.  We are extremely proud to be involved in this project.

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Allen Engineering is beginning its 21st year associated with the Space Coast Post of the Society of American Military Engineers (SAME).  During our 21 years, we have helped raise over $350,000 in scholarships and endowments.  We are extremely proud to be associated with SAME and its continued commitment to offer opportunities for students pursuing careers in the engineering field.


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During this period each poor family in the valley saw their income increase from 200 Soles per month to prostate procedures for enlarged prostate eulexin 250 mg 1 800 soles (J androgen hormone excess cheap 250mg eulexin with visa. In Kenya prostate volume normal purchase 250mg eulexin otc, women alone controlled dairy income in 50 percent of interviewed households mens health of the carolinas best eulexin 250mg, with husbands and wives jointly controlling income in another 25 percent of the cases. Results from a limited survey in two dairy business hub sites in Kenya show that increased milk production at household level translates into increased milk consumption by children and therefore improved nutrition. The challenge for farmers who intensify dairying relates to increased labour requirements for women. Recent calls for awareness raising and promotion of labour-saving technologies to mitigate possible negative impacts show recognition that family well-being and gender relations need attention as production scale rises from subsistence, to transforming, to commercial dairying. The dairy is five miles down an almost impassable track, and you would think milk would turn to butter long before it arrives. Yet the place is heaving with farmers waiting for their produce to be tested, carrying it in pails on trucks, on the backs of motorbikes or on their heads. The dairy opened only 18 months ago and may seem basic, yet it has just struck a deal to sell milk to an international processing plant in Nairobi. Two years ago he was scratching a living, supplementing his earnings from one cow, a native longhorn, with odd jobs outside farming. Now he has five cows, three of them Holsteins that give twice as much milk as the native breed. He rents extra land from his neighbour, has rebuilt his house, grows pineapples for export and has installed a biomass pump. Brazil, by investing heavily in research, has turned itself into the first tropical farm giant, joining the ranks of the temperate-food superpowers such as America, Europe and Canada. So it is possible to grow more food, more efficiently, on both a regional and a national scale. But can it be done on a global scale, which is what is needed to feed 9 billion people? Kabiyet Dairies was established in Kenya in august 2009 and presently has 2 802 smallholder farming family shareholders who delivered 837 079 litres of milk in December 2010. Education, training and information networks characterized dairy development projects in the last half century. Women with dairy earnings were able to refuse coolie work, stay home and allow their girls and boys to attend school. India now hosts 11 dairy science colleges, 31 veterinary colleges and over 80 agricultural universities (Mathur, 2000). The Centre provides vocational short courses and outreach training modules on the entire dairy chain, including training for trainers. While this chapter reviews the impact of project and programme interventions on nutrition and health, the nutritional aspects are addressed in much greater depth in Chapters 4, 5 and 7. During the literature review for this chapter, a gap was identified in scientific research on the impact of dairy-industry programmes on human health and nutrition. It is important to recognize that most dairy programmes do not have improved dietary intake and nutritional status as explicit goals and it is frequently assumed that such outcomes are automatic. This evidence gap is to some extent addressed in Chapter 7 of this book, which reviews available research on dairy production programmes and nutrition. Thus good nutritional outcomes can only be attained if an individual has access to a nutritionally adequate diet relative to his/her physiological requirements in combination with access to clean water and sanitation and adequate health and social care. A varied diet composed of sufficient quantities of diverse foods is the cornerstone of food security and key to avoiding both under- and overnutrition (obesity). While staple foods frequently provide the bulk of energy and protein, dietary variety is pivotal for human health, proper child growth and socio-economic development. In addition to staples, fruits, vegetables and legumes, some animalsourced foods such as dairy products, eggs and fish are essential in a healthy diet. Dietary recommendations for milk and dairy products continue to generate significant interest. Recommendations differ according to the nutritional needs of different age groups. Generally, larger quantities of milk and dairy are recommended for children and adolescents, pregnant and lactating women and the elderly, who have special requirements. As already discussed in Chapters 4 and 7, milk and dairy foods can make an important contribution to improving nutrition for women and children and are an important constituent in food products aimed at treating malnourished children. In livestock-keeping communities where milk is readily available milk and dairy products are fed preferentially to young children, whose nutritional requirements for growth and mental development are greatest between conception and two years of age. However, the possible impact of increased income and associated purchase of animal products and improved health care is seldom considered in such reports. In the Ethiopian Highlands, the introduction of improved technologies (cross-bred cows, improved feeding and management) made a significant contribution to food security and nutrition as well as to alleviating poverty (Tangka, Ouma and Staal, 1999). While agricultural programmes, including post-harvest processing, contribute to the quality and quantity of the food supply (Peduzzi, 1990; Soleri, Smith and Cleveland, 2000), nutritional objectives are seldom integrated with main objectives or monitored. An important observation is that women are the primary caregivers in households and many references indicate that income gained by women is directed towards family health, care and well-being. People in low-income countries spend an average of 55 percent of their expenditures on food, as compared with 16 percent in high-income countries (Regmi, 2001). Agricultural policies that reduce production costs, create incentives to produce more nutrient-rich and diversified crops and improve access to markets can improve food supply, nutrition and income (Chavas and Uriarte, 1999; Xinshen et al.

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The project was funded by Boehringer Ingelheim mens health 082013 quality eulexin 250 mg, who had no role in the development of the Delphi questions or the voting process prostate lump order 250mg eulexin otc. Twenty-nine percent of patients received personalized treatment according to prostate oncology kansas order eulexin 250mg amex these results mens health big book of exercises pdf cheap eulexin 250mg on-line. Some clinical features were found by gender in our population probably related to genomic differences linked to sex. Three months later she had another predominant neurologic episode of disorientation, aggression and aggravated dysarthria. Ten days after discharge, she returned with diffuse diarrhea and uncontrollable vomiting ending up dying a day later. The main mutations registered were exon 21 deletion (41%) and exon 19 deletion (4. Early diagnosis of small intestinal metastases is difficult because of the low incidence of clinically apparent symptoms. Method: A 69-yearold Chinese man presented for evaluation of a tumor in the right lower lung and mediastinal lymph node enlargement on clinical examination. Conclusion: Physicians must be aware of the possibility of intestinal metastases from primary lung cancer. With an accurate diagnosis and thorough evaluation, patients may benefit from targeted therapy. There are only a few data about the treatment results and toxicity of long-term treatment lasting 5 years or over. Here we present the data about another two patients, and updated data about the previously found seven patients. Characteristics of patients and the treatment results are summarised in the Table. Bronchoscopic biopsy over the endobronchial tumor was done and the pathology report showed squamous cell carcinoma. One month after treatment an initial tumor response was observed, however, a progression occurred after 3 months of treatment. Despite last efforts, the overall survival rate at five years after diagnosis is under 15%. Suicide gene therapy is an interesting technology which consists in expressing a toxic gene into tumor cells. To determine the ability to direct the expression of the suicide gene on this system, we used a lung cancer cell line and a non-tumor, lung tissue one. Result: Two cases developed bronchial fistula during the treatment of anlotinib alone, suggesting that the adverse effects mainly related to the antiangiogenics effect of it and causing ischemic necrosis. Other possible factors include: central lung cancer, squamous cell carcinoma, cachexia, multi-line treatment, long diameter of tumor5cm) and cavity formation, radiotherapy, accompanied with underlying diseases easy to complicated with infection, such as diabetes. Hereby we present our experience with a case of adenocarcinoma lung with brain metastasis on presentation who has received multiple lines of treatment approach and leading a happy and hearty life after 8 years(96 months) of diagnosis. After six months,he developed recurrence at brain,for which surgical excision of the brain lesion(metastatectomy) was done followed by reirradiation to brain. Again he developed brain recurrence following which he received six cycles of Pemetrexed and Carboplatin followed by six cycles of maintenance Inj Pemetrexed. Recurrence of brain lesion was again encountered after four months for which he received six cycles of Inj Bevacizumab+ Nab-Paclitaxel + Carboplatin. Then after one year,on recurrence in brain with surgical excision of the tumor and subsequent evaluation it was found that he had T790M mutation and hence was planned for Tab Osimertinib. Patient is doing fine till date with a followup period of 96 months since upfront presentation with brain metastasis. Hence biopsy and identifying the druggable targets have become of prime importance in managing lung malignancies. New therapeutics, such as tyrosine kinase inhibitors or immunotherapy may improve survival, but these treatments are only effective in small cohorts of patients. Thus, hopes of improving survival of lung cancer patients are related to the advent of novel therapeutic strategies. Result: Our case is a 60-year-old patient with no comorbidities who had presented in 2012 a left dorsal parietal mass, he was operated on, the histopathological examination concluded to a desmoid tumor. He presented in 2015 a tumor recurrence for which he was again operated and put under Celecoxib for one year, after the clinical and radiological progression, he was put under Tamoxifen, for 2 years. Conclusion: this case study allowed us to support the efficacy of Sorafenib, currently being tested (Study Alliance A91105) in the treatment of recurrent or locally advanced desmoid tumors. He was given Gefitinib, but the diseased progressed within 2 months and continued with Platinum based regimen with survival of 9 months. He was given Erlotinib, but the diseased progressed within 2 months and refused to be given chemotherapy, with survival of 5 months since diagnosis. Tolba Oregon Health & Science University, Portland/United States of America Method: Section not applicable Result: Section not applicable Conclusion: Our case report illustrates a real-life example of how spatiotemporal differences in the tumor micro-environment could give rise to intra-tumor heterogeneity and shape response to therapy. Imaging performed six months after starting erlotinib revealed resolution of her residual lung disease and left precentral gyrus brain metastasis and she continued erlotinib for the next 7-years until 03/2017, when she presented with headaches and ataxia. However, the spectrum of side effects in different therapy time might exist heterogeneity. Further perspective trials and data are warranted to confirm this conclusion and improve clinical medication guidance. Result: the patient was treated with pembrolizumab (firstline therapy) and then carboplatin, pemetrexed and bevacizumab (second-line therapy). Nevertheless, the disease was progressed, so dabrafenib plus trametinib were used for the third line therapy.

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These volunteers androgen releasing hormone generic 250mg eulexin amex, representing all relevant disciplines mens health power training generic 250mg eulexin mastercard, are organized into disease teams chaired by leading clinicians prostate zonal anatomy diagram 250 mg eulexin sale. These teams make recommendations for change in the staging system based on available evidence supplemented with expert consensus man health tips in urdu order 250mg eulexin amex. Supporting these teams is a panel of expert statisticians who provide critical support in evaluation of existing data and in analysis of new data when this is available. For some diseases, particularly less common cancers, there are few outcome data available. These staging systems are based on what limited data are available, supplemented by expert consensus. Though potentially imperfect, these disease schemas are critical to allow the collection of standardized data to support clinical care and for future evaluation and refinement of the staging system. In addition, groups have been established to collect very large international data sets to refine staging. Although such statements are misguided, the reality is that the anatomic extent of disease only tells part of the story for many cancer patients. The question of including nonanatomic prognostic factors in staging has led to intense debate about the purpose and structure of staging. This shift away from purely anatomic information has been extended in the current edition. Examples include the mitotic rate in staging gastrointestinal stromal tumors and prostate-specific antigen and Gleason score in staging prostate cancer. In the future, the discovery of new markers will make it necessary to include these markers in staging and will likely require the development of new strategies beyond the current grouping systems. That said, it must also be clearly stated that it is critical to maintain the anatomic base to cancer staging. In addition, it is necessary to have clear links to past data to assess trends in cancer incidence and the impact of advances in screening and treatment and to be able to apply stage and compare stage worldwide in situations where new nonanatomic factors are not or cannot be collected. These factors are not used to define the T, N, and M components, which remain purely anatomic. Where they are used to define groupings, there is always a convention for assigning a group without the nonanatomic factor. This work involved many professionals in all fields in the clinical oncology, cancer registry, population surveillance, and statistical communities. It is hard to single out individuals, but certain people were central to this effort. Irvin Fleming, to whom we dedicate this Manual, showed the leadership and the vision over a decade ago that led to the development of the Collaborative Stage Data Collection System. The work of our publisher Springer provided the resources to support this work and the patience needed as the Task Forces and editors finished their work. The many cancer registrars and the Collaborative Stage Version 2 Work Group who worked on the disease teams kept us all properly focused. The two organizations have worked together at every level to create a staging schema that remains uniform throughout. Classification and staging of cancer enable the physician and cancer registrar to stratify patients, which leads to better treatment decisions and the development of a common language that aids in the creation of clinical trials for the future testing of cancer treatment strategies. A common language of cancer staging is mandatory in order to realize the important contributions from many institutions throughout the world. The driving force behind the organization of this body was a desire to develop a system of clinical staging for cancer that was acceptable to the American medical profession. The latter organization became most active in the field through its Committee on Clinical Stage Classification and Applied Statistics (1954). In addition, a classification of the stages of cancer was utilized as a guide for treatment and prognosis and for comparison of the end results of cancer management. The second edition of this manual (1983) updated the earlier edition and included additional sites. The expanding role of the American Joint Committee in a variety of cancer classifications suggested that the original name was no longer applicable. In addition, accurate staging is necessary to evaluate the results of treatments and clinical trials, to facilitate the exchange and comparison of information among treatment centers, and to serve as a basis for clinical and translational cancer research. At a national and international level, the agreement on classifications of cancer cases provides a method of clearly conveying clinical experience to others without ambiguity. Differences among these systems stem from the needs and objectives of users in clinical medicine and in population surveillance. However, changes in staging systems may make it difficult to compare outcomes of current and past groups of patients. Because of this, the organizations only make these changes carefully and based on the best possible evidence. This provides sufficient time for implementation of changes in clinical and cancer registry operations and for relevant examination and discussion of data supporting changes in staging. Cancer staging is historically based solely on the anatomic extent of cancer and remains primarily anatomic. However, an increasing number of nonanatomic factors about a cancer and its host provide critical prognostic information and may predict the value of specific therapies. Among those factors known to affect patient outcomes and/or response to therapy are the clinical and pathologic anatomic extent of disease, the reported duration of signs or symptoms, gender, age and health status of the patient, the type and grade of the cancer, and the specific biological properties of the cancer.

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Most of this growth is taking place in smallholder or backyard systems with low biosecurity levels mens health april 2013 purchase 250 mg eulexin, posing clear disease challenges prostate procedures for enlarged prostate buy cheap eulexin 250 mg on line. Prevention and control efforts should therefore focus on improved husbandry practices and biosecurity prostate 140 purchase 250 mg eulexin with amex, and protection of areas not affected by the disease (through regulated trade and swine sector development programmes that stress awareness and prevention measures) prostate cancer surgery buy eulexin 250mg low price. East Africa African swine fever was first detected in Kenya in 1909 following the introduction into the country of European domestic swine (Montgomery, 1921). In East Africa, the virus is maintained in a sylvatic cycle between warthogs and Ornithodoros ticks living in their burrows. The first outbreaks occurred in pigs belonging to European settlers, and it was found that by erecting fencing around farms to exclude warthogs and ticks, pigs could be farmed safely. However, pig farming has since increased in popularity in the region and large numbers of animals are kept 8 African swine fever: detection and diagnosis in insecure or free-range systems. Increased peri-urban pig production is reflected in outbreaks around bigger cities such as Kampala, Nairobi, Mombasa, and Dar es Salaam. The existence of a cycle of maintenance between domestic pigs and Ornithodoros in Kenya has also been identified (Gallardo et al. Southern Africa the sylvatic cycle involving warthogs is present in the northern parts of the subregion (Botswana, Malawi, Mozambique, Namibia, Zambia, Zimbabwe and the northeastern parts of South Africa). In Malawi and Mozambique, a cycle involving domestic pigs and ticks has been identified or demonstrated to be highly likely. Zimbabwe reported its first outbreak in free-range pigs in 2015 after more than 20 years of absence. In 2007, Mauritius experienced an incursion that was eradicated the following year. The subregion shows a high level of genetic variation (Figure 2) linked to the presence of the sylvatic cycle. Central Africa the Democratic Republic of Congo and the Congo Republic are historically endemically infected. It is likely that the sylvatic cycle is involved, at least in parts of those countries, as infected warthogs have been reported in Congo Republic (Plowright et al. Other countries in the region have also reported outbreaks, notably Cameroon, which experienced its first incursion in 1982, not long after the pig population doubled. In 1973, the island country of Sao Tome and Principe experienced outbreaks that were rapidly eradicated. No sylvatic cycle involving wild suids and/or Ornithodoros ticks in maintaining the virus has been demonstrated. Only genotype I is circulating, suggesting introduction rather than evolution of the virus in the region (Figure 2). The disease spread quickly throughout the Caucasus (Armenia in 2007 and Azerbaijan in 2008) and into the Russian Federation (2007). In the past few years, the disease has progressively spread westwards, entering Ukraine (2012), Belarus (2013), the European Union (Lithuania, Poland, Latvia and Estonia, 2014), and Moldova (2016) (Figure 6). Swill feeding and improper disposal of carcasses then expose susceptible pig populations. How they do so is not completely clear, but seems to depend largely on the population density of wild boar and their interaction with low-biosecurity pig production (free-ranging and scavenging pigs in particular). Carcasses of infected animals and food waste containing infected pork products are also thought to be involved. It also hit the Caribbean (Cuba, 1971 and 1980; the Dominican Republic, 1978; and Haiti, 1979) and Brazil (1978). More recently, a wild boar cycle has been described, which may sometimes be involved in the latter. The sylvatic cycle occurs only in parts of Africa and involves warthogs and ticks of the Ornithodoros moubata complex. Transmission from the sylvatic cycle (African wild suids) to the domestic cycle (farmed pigs) occurs via indirect transmission by ticks. This can happen where pigs and warthogs share common grounds, particularly when warthogs establish burrows on farms, or when ticks are brought back to villages through the carcasses of warthogs killed for food. Warthogs are infected by Ornithodoros bites in the first 6-8 weeks of life, while in the burrow (Figure 8). Following a short period when the virus is present in their bloodstream (2-3 weeks), the young warthogs recover, showing no clinical signs. Virus can usually be recovered from the lymph nodes of warthogs of any age, although viraemia sufficient to infect ticks has only been found in neonates from burrows. It is likely that warthogs experience repeated infections when ticks feed on them, with low levels of virus remaining latent in the lymph nodes. Tick populations can remain infected and infective for long periods due to transstadial, venereal and transovarial transmission of the virus in the tick population, allowing the virus to persist even in the absence of viraemic hosts. Infected ticks play an important role in the long-term maintenance of the disease, surviving for months in burrows and up to several years after feeding on an infected host. The cycle has also been described in parts of Africa, where it is well documented in Malawi, Madagascar and Mozambique, although ticks probably do not play a prominent role in virus transmission within pig populations (Haresnape & Mamu, 1986; Quembo et al. However, what happens in the laboratory does not necessarily reflect what happens under field conditions. For Ornithodoros ticks to become competent vectors under field conditions, they need pigs as their preferred hosts, failing which natural transmission is likely to remain limited. Vector competence may also vary greatly inside species, or groups of closely related species, according to distinct population features.

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Another approach is to prostate mass discount 250mg eulexin visa directly fortify milk with fish oils (further examined in Section 5 healthy prostate usa laboratories discount eulexin 250 mg with mastercard. Milk is considered to prostate cancer wristband eulexin 250 mg overnight delivery be an excellent source of essential amino acids for human nutrition mens health journal generic eulexin 250 mg online, growth, and development (Kanwar et al. The impact of milk protein intake on body composition has not been fully elucidated, particularly at different life stages. Although some studies have reported that whey proteins and bioactive peptides in dairy may contribute to weight management, the evidence is contradictory. Traditionally, whey was considered the low-value by-product of cheese production, but in recent decades, whey components have attracted increasing commercial interest (Bulut Solak and Akin, 2012). Whey is the soluble fraction of milk that is separated from casein during cheese-making and casein manufacture in the dairy industry. The whey fraction contains a variety of proteins which can be separated by processes such as ultrafiltration and reverse osmosis to produce whey-protein concentrates. Whey proteins, in addition to delivering amino acids, are reported to be involved in protection against infections, immune enhancement and development of the gut (Kanwar et al. Recently, it has been suggested that it may have beneficial effects on sleep, mood and cognition because of its role in increasing serotonin levels (Korhonen, 2009a; Camfield et al. A number of health characteristics have been suggested for -lactoglobulin, including antiviral and anticarcinogenic effects (Chatterton et al. Lactoferrin, an iron-binding whey protein, has been associated with positive antimicrobial effects, immune modulation and modulation of the gut microbiota (Kanwar et al. A recent meta-analysis on the efficacy of lactoferrin in the eradication of Helicobacter pylori infection concluded that lactoferrin may have the potential to reduce H. Heliobacter pylori is the causative agent of peptic ulcer diseases and chronic gastritis and is an important risk factor for development of gastric cancer (Salih, 2009); the global prevalence of H. The safety and validity of increased protein intakes for both weight maintenance and muscle synthesis have been subjects of considerable debate and some health professionals, media and diet books advise consuming diets high in protein despite the lack of scientific data on the safety of increasing protein consumption (Bilsborough and Mann, 2006). Protein fragments: bioactive peptides Recent research has shown that milk proteins can act as precursors of bioactive peptides, which are protein fragments varying in size from two to 20 amino acids. Although research indicates that the peptides can exert a range of biological activities, depending on the amino-acid sequence, their physiological impact in humans is still unclear (Silva and Malcata, 2005; Nagpal et al. Possible health benefits of milk-protein-derived bioactive peptides are presented in Figure 5. As discussed in Chapter 4, lactose intolerance, which is caused by insufficient amounts or activity of lactase in the human intestine, can result in varying degrees of abdominal discomfort, bloating, diarrhoea and flatulence (Wilt et al. They are also found in bakery products, beverages, confectionery, dressings, sauces, cereals and sports beverages. Edible lactose is often used in foods such as bread, confectionaries and infant formula, as well as in non-food applications such as animal feed and fermentation-culture media. Casein-derived peptides have been used in pharmaceutical preparations and as dietary supplements (Nagpal et al. However, caution must be taken in labelling the final product as trace dairy ingredients may be present in the final product. This is significant for components such as cow-milk protein that can cause an adverse allergic reaction in susceptible consumers. It is imperative that any associated risks with a dairy component are fully understood and communicated to the consumer. In order to achieve a high level of protection for food-allergic consumers, allergens such as cow-milk protein should be indicated on the label of food products and alcoholic beverages such as wine; cow milk and/or its derivatives may be used as processing aids in wine-making and traces may remain in the final product (Kirschner et al. Although processes such as fermentation have been traditionally used, the dairy sector has developed techniques to produce a diverse range of milk-based products and dairy ingredients. For example, lactose can be removed by hydrolysis or by physical means such as ultrafiltration and chromatography. It is also possible to enrich and fortify dairy products with nutrients such as iron, plant sterols and stanols. Broadly, dairy products can be categorized as basic products, such as fermented milk, cheese and yoghurt, and value-added products, such as low-fat and fortified milks (Nagpal et al. Some of the health implications associated with fermented and fortified dairy products are outlined in the next section. Milk fermentation is one of the oldest known food preservation techniques, and involves the transformation of liquid milk into a range of valueadded products by growth of micro-organisms in the milk and/or their activities on milk. Micro-organisms that perform the fermentation process may produce beneficial metabolites (biogenic effect) or may themselves interact with the host in a positive manner (the probiotic effect) (Stanton et al. The probiotic concept49 was first introduced in the early 1900s by Russian scientist Elie Metchnikoff of the Pasteur Institute, who hypothesized that the presence of lactose-fermenting bacteria in the colon could prolong life (Metchnikoff, 1908; Candy et al. Fermented milk products have traditionally been associated with a series of health-promoting properties. In Eastern Europe, the fermented dairy product kephir has a long history of purported health benefits (Ribeiro and Ribeiro, 2010). The Maasai, a Nilo-Hamitic tribe living a nomadic life in the East African Rift Valley of Southern Kenya and Northern Tanzania, consume kule naoto, a traditional fermented milk product (Mathara et al.


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