Contact Allen Engineering

News goicon

New Project News

AEI currently utilizes a RIEGL VZ400 Terrestrial Laser Scanner on various job sites.  This proecss utilizes a high accuracy 3D terrestrial LiDAR unit.  The data collected will be brought into a feature extraction software, TopoDOT.  TopoDOT utilizes a variety of tools to identify adn quickly extrapolate features within pointcloud data.  All features can then be imported into an AutoCAD drawing file.  AEI can provide an accurate 3D pointcloud of terrain plus any existing building or structures.  The pointcloud can also be converted for Building Information Models.

More Project News

Allen Engineering is involved with the civil design and surveying for the new park in Palm Bay, Flordia.  This Regional Park will feature 150 full service campsite hookups and is scheduled to break ground in 2018.  We are extremely proud to be involved in this project.

AEI News

Allen Engineering is beginning its 21st year associated with the Space Coast Post of the Society of American Military Engineers (SAME).  During our 21 years, we have helped raise over $350,000 in scholarships and endowments.  We are extremely proud to be associated with SAME and its continued commitment to offer opportunities for students pursuing careers in the engineering field.


"Buy serophene 25mg low cost, menopause show."

By: Mark D. Miller, MD

  • S. Ward Casscells Professor, Department of Orthopaedics, University of Virginia, Charlottesville, Virginia


If the patient later has a problem that could be related to breast cancer vs testicular cancer buy serophene 25 mg with mastercard the transfusion menopause facts buy serophene 50mg amex, the records should show who ordered the products and why menstrual cycle day 4 serophene 50 mg for sale. Monitoring the transfused patient It is essential to womens health toning station cheap 50 mg serophene fast delivery take baseline observations and to ensure that the patient is being monitored during and after the transfusion in order to detect any adverse event as early as possible. Severe reactions most commonly present during the first 15 minutes of a transfusion. All patients and, in particular, unconscious patients should be monitored during this period and for the first 15 minutes of each subsequent unit. If a unit is not completed within four hours, discontinue its use and dispose of the remainder through the clinical waste system. Acute transfusion reactions If the patient appears to be experiencing an adverse reaction, stop the transfusion and seek urgent medical assistance. In the case of a suspected transfusion reaction, do not discard the blood pack and infusion set, but return them to the blood bank for investigation. With experience, these can be recognized so that transfusions are not delayed or stopped unnecessarily. Initial management and investigation When an acute reaction first occurs, it may be difficult to decide on its type and severity as the signs and symptoms may not initially be specific or diagnostic. However, with the exception of allergic urticarial and febrile non-haemolytic reactions, all are potentially fatal and require urgent treatment. In an unconscious or anaesthetized patient, hypotension and uncontrolled bleeding may be the only signs of an incompatible transfusion. In a conscious patient undergoing a severe haemolytic transfusion reaction, signs and symptoms may appear within minutes of infusing only 5­10 ml of blood. If there is any discrepancy, stop the transfusion immediately and consult the blood bank. In order to rule out any possible identification errors in the clinical area or blood bank, stop all transfusions in the same ward or operating room until they have been carefully checked. In addition, request the blood bank to stop issuing any blood for transfusion until the cause of the reaction has been fully investigated and to check whether any other patient is receiving transfusion, especially in the same ward or operating room, or at the same time. See pages 62­65 for the signs and symptoms, possible causes and management of the three broad categories of acute transfusion reaction to aid in immediate management. Page 66 summarizes the drugs and dosages that may be needed in managing acute transfusion reactions. If hypotensive: s Give further saline 20­30 ml/kg over 5 minutes s Give inotrope, if available. If you suspect a severe life-threatening reaction, seek help immediately from the duty anaesthetist, emergency team or whoever is available and skilled to assist. This almost always arises from: s Errors in the blood request form s Taking blood from the wrong patient into a pre-labelled sample tube s Incorrect labelling of the blood sample tube sent to the blood bank s Inadequate checks of the blood against the identity of the patient before starting a transfusion. Bacterial contamination and septic shock 1 Bacterial contamination affects up to 0. Yersinia) s Improper handling in blood processing s Defects or damage to the plastic blood pack s Thawing fresh frozen plasma or cryoprecipitate in a waterbath (often contaminated). Anaphylactic reaction 1 A rare complication of transfusion of blood components or plasma derivatives. Delayed complications of transfusion Delayed haemolytic transfusion reactions Signs and symptoms 1 Signs appear 5­10 days after transfusion: s Fever s Anaemia s Jaundice s Occasionally haemoglobinuria. Post-transfusion purpura 1 A rare but potentially fatal complication of transfusion of red cells or platelet concentrates, caused by antibodies directed against platelet-specific antigens in the recipient. Signs and symptoms s Signs of bleeding s Acute, severe thrombocytopenia 5­10 days after transfusion, defined as a platelet count of less than 100 x 10 9/L. Management Management becomes clinically important at a platelet count of 50 x 109/L, with a danger of hidden occult bleeding at 20 x 10 9/L. Prevention Gamma irradiation of cellular blood components to stop the proliferation of transfused lymphocytes. Iron overload There are no physiological mechanisms to eliminate excess iron and thus transfusion-dependent patients can, over a long period of time, accumulate iron in the body resulting in haemosiderosis. Signs and symptoms Organ failure, particularly of the heart and liver in transfusion-dependent patients. Management and prevention 1 Iron-binding agents, such as desferrioxamine, are widely used to minimize the accumulation of iron in transfusion-dependent patients (see pp. Since a delayed transfusion reaction may occur days, weeks or months after the transfusion, the association with the transfusion may easily be missed. Morbidity and mortality tend to be high among such patients, not because of the large volumes infused, but because of the initial trauma and the tissue and organ damage secondary to haemorrhage and hypovolaemia. It is often the underlying cause and consequences of major haemorrhage that result in complications, rather than the transfusion itself. However, administering large volumes of blood and intravenous fluids may itself give rise to the following complications. Under normal circumstances, the body can easily neutralize this acid load from transfusion. The routine use of bicarbonate or other alkalizing agents, based on the number of units transfused, is unnecessary. Hyperkalaemia the storage of blood will result in a small increase in extracellular potassium concentration, which will increase the longer it is stored. This rise is rarely of clinical significance, other than in neonatal exchange transfusions. Use the freshest blood available in the blood bank and which is less than 7 days old.


  • The edges of your intestines that are sewn together come open (anastomotic leak -- this may be life-threatening)
  • Try to make sure that the person has indeed been poisoned. It may be hard to tell. Some signs include chemical-smelling breath, burns around the mouth, difficulty breathing, vomiting, or unusual odors on the person. If possible, identify the poison.
  • Apply sunscreen at least 30 minutes before going outside, and reapply it frequently, especially after swimming.
  • Amount swallowed
  • Marfan syndrome
  • Fear of "going crazy"
  • Alert to voices
  • Blood clots in the legs that may travel to the lungs

buy serophene 25mg low cost

Nerve axons that have been compromised after inflammation women's health center garden city 25mg serophene free shipping, stretch women's health jokes cheap serophene 100 mg fast delivery, or crush injury can develop abnormal sodium channels women's health clinic queen elizabeth buy serophene 50 mg line. Within this context women's health tips exercise discount serophene 25 mg on-line, anxiety, loss of self-efficacy, fear of pain, depression, and other psychological states are also considered to be facilitators or inhibitors of neurologic transmission. Ovulationand/or menstrualsuppressionisespeciallyhelpfulinpatients who have midcycle, premenstrual, or menstrual exacerbation of pain, or in those who have ovarian pathology,suchasperiovarianadhesionsorrecurrent functional cyst formation. The patient should be given regular follow-up appointments, and should not be told to call only if the pain persists. Lysis of adhesionsisalsousuallynonproductive,withthepossibleexceptionofthesituationswherethesiteofadhesions, as visualized by the laparoscope, specifically coincideswiththelocalizationofpain. Without proof of organic pathology or a reasonable functional explanation for the pelvic pain, a thorough psychosomatic evaluation should be carried out before any surgical procedure is considered. Acupuncturehasbeenusedsuccessfullyfordysmenorrhea, and trigger-point injections and nerve blockswithlocalanestheticshavebeenusedsuccessfully for neuropathic and musculoskeletal pain. A significant percentage of patients with pelvic pain have abdominal wall trigger points or nerve entrapments that respond to weekly or biweekly injections of a local anesthetic (usually up to five injections is sufficient) combined with alterations of activity or modification of behaviors that affect the area of pain. Injectionoflocalanestheticintomyofascial trigger points (Figure 21-3) may abolish pain by lowering the impulses from the area of referred pain, therebydiminishingtheafferentimpulsesreachingthe dorsal horn to a level below the threshold for pain transmission(buttheexactmechanismisnotknown). Repeated local anesthetic nerve blocks of areas of nerve impingement/entrapment combined with instructions to patients about alteration in physical activityandorphysicaltherapycanbehelpful. Along withnervethresholdalteringmedications,theseinterventions can down regulate neural hypersensitivity andpermanentlydecreaseoreliminatepain. Infectious diseases of the reproductive and urinary tracts are interesting and challenging disorders in gynecology. Infections of the vulva, vagina, and cervix (lower reproductive tract) and the uterine corpus, fallopian tubes, and ovaries (upper reproductive tract) are the mostcommongynecologicproblems. The diagnosis andmanagementofcommonreproductiveandurinary tract infections in both nonpregnant and pregnant womenarediscussedinthischapter. The normal vaginal flora is mostly aerobic, with an average of six different species of bacteria, the most common of which is the hydrogen peroxide­producing lactobacillus. The microbiology of the vagina is determined by factors that affect the ability of bacteria to survive. The pH of the normal vagina is lower C H A P T E R 22 Infectious Diseases of the Female Reproductive and Urinary Tract 277 than 4. Vaginalepithelialcellsbreakdown glycogentomonosaccharides,whichcanbeconverted by the cells themselves, and by lactobacilli to lactic acid. Microscopy of normal vaginal secretions reveals many superficial epithelial cells, few white blood cells (less than 1 per epithelial cell), and few, if any, clue cells. Clue cells are superficial vaginal epithelial cells with adherent bacteria, usually Gardnerella vaginalis, which obliterate the crisp cell border when visualized microscopically (Figure 22-1). Gram stain reveals normal superficial epithelial cells and a predominance of gram-positive rods (lactobacilli). The additionofpotassiumhydroxidetothevaginalsecretions (the "whiff" test) releases a fishy, amine-like odor. Clinicianswhoareunabletoperformmicroscopy can use alternative diagnostic tests such as a pH and amines test card, detection of G. Many clinicians prefer intravaginal treatment to avoid systemic side effects such as mild tomoderategastrointestinalupsetandanunpleasant taste. Treatment of the male sexual partner does not improve therapeutic response and therefore is not recommended. Clindamycin cream is oil-based and might weaken latex condoms and diaphragms for 5 days after use (refer to clindamycin product labeling for additional information). Note the presence of a clue cell, which is an epithelial cell with "serrated" edges caused by bacteria (arrows). Forthisreason,nucleicacidamplification testing is recommended when trichomoniasis is suspectedbutnotconfirmedbymicroscopy. Both a single-dose (2g orally)andamultidose(500mgtwicedailyfor7days) regimen are highly effective and have cure rates of about95%. Womenwhodonotrespondtoinitialtherapyshould be treated again with metronidazole, 500mg, twice dailyfor7days. Ifrepeatedtreatmentisnoteffective, thepatientshouldbetreatedwithasingle2-gdoseof metronidazole once daily for 5 days or tinidazole 2g, inasingledosefor5days. Patientswhodonotrespond torepeatedtreatmentwithmetronidazoleortinidazole andforwhomthepossibilityofreinfectionisexcluded should be referred for expert consultation. In these uncommon refractory cases, an important part of management is to obtain cultures of the parasite to determine its susceptibility to metronidazole and tinidazole. Theextensiveareas of pruritus and inflammation, often associated with minimal invasion of the lower genital tract epithelial cells,suggestthatanextracellulartoxinorenzymemay playaroleinthepathogenesisofthisdisease. Pregnancy and diabetes are associated with a qualitative decrease in cellmediated immunity, leading to a higher incidence of candidiasis. Thetransmissionrateishigh;70% of men contract the disease after a single exposure to an infected woman, which suggests that the rate of male-to-female transmissionisevenhigher. Bacterial vaginosiscanbe diagnosed in as many as 60% of patients with trichomonasvaginitis. Trichomonas vaginitis is associated with a profuse, purulent, malodorous vaginal discharge that may be accompanied by vulvar pruritus. Inpatientswithhigh concentrations of organisms, a patchy vaginal erythema and colpitis macularis ("strawberry" cervix) may be observed. Treatment with azoles results in relief of symptoms and negative cultures in 80-90% of patients.

Buy serophene 100 mg on-line. 10 Healthiest foods for pregnant women | Best healthy foods diet during pregnancy.

buy discount serophene 25 mg on line

Thrombin (34 kDa) pregnancy 24 100 mg serophene for sale, a serine protease formed by the prothrombinase complex pregnancy hormones purchase serophene 100mg with mastercard, hydrolyzes the four Arg-Gly bonds between the fibrinopeptides and the and portions of the A and B chains of fibrinogen (Figure 51­5A) pregnancy 19 weeks serophene 100 mg overnight delivery. The release of the fibrinopeptides by thrombin generates fibrin monomer women's health issues pregnancy week by week generic 50 mg serophene free shipping, which has the subunit structure (,)2. It is the formation of this insoluble fibrin polymer that traps platelets, red cells, and other components to form the white or red thrombi. This initial fibrin clot is rather weak, held together only by the noncovalent association of fibrin monomers. This factor is a highly specific transglutaminase that covalently cross-links fibrin molecules by forming peptide bonds between the amide groups of glutamine and the -amino groups of lysine residues (Figure 51­5B), yielding a more stable fibrin clot with increased resistance to proteolysis. Levels of Circulating Thrombin Must Be Carefully Controlled or Clots May Form Once active thrombin is formed in the course of hemostasis or thrombosis, its concentration must be carefully controlled to prevent further fibrin formation or platelet activation. Thrombin circulates as its inactive precursor, prothrombin, which is activated as the result of a cascade of enzymatic reactions, each converting an inactive zymogen to an active enzyme and leading finally to the conversion of prothrombin to thrombin (Figure 51­1). At each point in the cascade, feedback mechanisms produce a delicate balance of activation and inhibition. The second means of controlling thrombin activity is the inactivation of any thrombin formed by circulating inhibitors, the most important of which is antithrombin (see below). The Activity of Antithrombin, an Inhibitor of Thrombin, Is Increased by Heparin Four naturally occurring thrombin inhibitors exist in normal plasma. The most important is antithrombin, which contributes approximately 75% of the antithrombin activity. The endogenous activity of antithrombin is greatly potentiated by the presence of sulfated glycosaminoglycans (heparans) (Chapter 48). These bind to a specific cationic site of antithrombin, inducing a conformational change and promoting its binding to thrombin as well as to its other substrates. This is the basis for the use of heparin, a derivatized heparan, in clinical medicine to inhibit coagulation. The anticoagulant effects of heparin can be antagonized by strongly cationic polypeptides such as protamine, which bind strongly to heparin, thus inhibiting its binding to antithrombin. They can be administered subcutaneously at home, have greater bioavailability than unfractionated heparin, and do not need frequent laboratory monitoring. Individuals with inherited deficiencies of antithrombin are prone to develop venous thrombosis, providing evidence that antithrombin has a physiologic function and that the coagulation system in humans is normally in a dynamic state. Thrombin is involved in an additional regulatory mechanism that operates in coagulation. It combines with thrombomodulin, a glycoprotein present on the surfaces of endothelial cells. A genetic deficiency of either protein C or protein S can cause venous thrombosis. These proteins, all of which are synthesized in the liver, are dependent on the Ca2+-binding properties of the Gla residues for their normal function in the coagulation pathways. The coumarins act by inhibiting the reduction of the quinone derivatives of vitamin K to the active hydroquinone forms (Chapter 44). Thus, the administration of vitamin K will bypass the coumarin-induced inhibition and allow the post-translational modification of carboxylation to occur. Reversal of coumarin inhibition by vitamin K requires 12­24 h, whereas reversal of the anticoagulant effects of heparin by protamine is almost instantaneous. Heparin and warfarin are widely used in the treatment of thrombotic and thromboembolic conditions, such as deep vein thrombosis and pulmonary embolus. Heparin is administered first, because of its prompt onset of action, whereas warfarin takes several days to reach full effect. Their effects are closely monitored by use of appropriate tests of coagulation (see below) because of the risk of producing hemorrhage. The same Arg-Val bond is cleaved by all plasminogen activators to give the two-chain plasmin molecule. Fibrin Clots Are Dissolved by Plasmin As stated above, the coagulation system is normally in a state of dynamic equilibrium in which fibrin clots are constantly being laid down and dissolved. Plasmin, the serine protease mainly responsible for degrading fibrin and fibrinogen, circulates in the form of its inactive zymogen, plasminogen (90 kDa), and any small amounts of plasmin that are formed in the fluid phase under physiologic conditions are rapidly inactivated by the fast-acting plasmin inhibitor, 2-antiplasmin. Plasminogen binds to fibrin and thus becomes incorporated in clots as they are produced; since plasmin that is formed when bound to fibrin is protected from 2-antiplasmin, it remains active. Activators of plasminogen of various types are found in most body tissues, and all cleave the same Arg-Val bond in plasminogen to produce the two-chain serine protease, plasmin (Figure 51­6). The specificity of plasmin for fibrin is another mechanism to regulate fibrinolysis. Via one of its kringle domains, plasmin (ogen) specifically binds lysine residues on fibrin and so is increasingly incorporated into the fibrin mesh as it cleaves it. Neither plasmin nor the plasminogen activator can remain bound to these degradation products, and so they are released into the fluid phase, where they are inactivated by their natural inhibitors. There Are Several Hereditary Bleeding Disorders, Including Hemophilia A Inherited deficiencies of the clotting system that result in bleeding are found in humans. The most common hereditary bleeding disorder is von Willebrand disease, with a prevalence of up to 1% of the population. During hemostasis or thrombosis, they become activated and help form hemostatic plugs or thrombi. Three major steps are involved: (1) adhesion to exposed collagen in blood vessels, (2) release (exocytosis) of the contents of their storage granules, and (3) aggregation. They release the contents of their storage granules (the dense granules and the alpha granules); secretion is also stimulated by thrombin. In this instance, thrombin acts as the external chemical messenger (stimulus or agonist). The interaction of thrombin with its G protein­coupled receptors stimulates the activity of an intracellular phospholipase C.


  • Deafness mesenteric diverticula of small bowel neuropathy
  • Schinzel Giedion midface retraction syndrome
  • Multiple sclerosis ichthyosis factor VIII deficiency
  • Lactate dehydrogenase deficiency type C
  • Jumping Frenchmen of Maine
  • Pfeiffer Kapferer syndrome
  • Aplastic anemia
  • Familial Mediterranean fever


  • https://www.medrxiv.org/content/10.1101/19000851v1.full.pdf
  • https://www.longdom.org/open-access/complication-of-cirrhosis-portal-hypertension-a-review-2167-0889-1000188.pdf
  • https://numerons.files.wordpress.com/2012/04/application-of-psychology-to-educational-field.pdf
  • https://www.ci2i.research.va.gov/CI2IRESEARCH/docs/structured_evidence_review.pdf